International Internal Medicine Journal(IIMJ)

Department of Pharmacy, Faculty of Medical Sciences, Al-Jazeera University, Ibb City, Yemen

Publications

• Research Article   
  Nephroprotective Activity of Ethanolic Leaves Extract of Vachellia origena (Hunde) Kyal. & Boatwr. (Fabaceae) on Paracetamol-Induced Nephrotoxicity in Male Guinea Pigs
  Author(s): Mohammed S. Mansour Saif, Warda Mohamed Abdu Kaidama*, Abdulrahman A. Alahdal, Ahmed A.A. Al-Nawah, Ali M.A. Alshaweri, Ameen N.A. Al-Hasani, Ayman A.M. Al-Muntasir, Basem A.A. Al-Badwi, Hesham A.S. Shams Aldeen, Mohammed A.M. Mahdi, Osama E.A. Al-Duais and Taher E.S. Al faqeeh and Yasser A.A. Al-Hajj
  
  Vachellia origena is a medicinal plant found in J. Saber, Alturba, Ibb, Dhamar, Sanaa, Haraz, Shibam and Yafea. They are utilized therapeutically to address many conditions, including antibacterial, antifungal, and antioxidant applications. This study aimed to investigate the preventive potential of V. origena against paracetamol-induced kidney injury in male guinea pigs. Thirty-five male guinea pigs (350–650 g) were randomly assigned to seven groups, each including five guinea pigs. Group I served as the control group. Group II was administered PCM (500 mg/kg) exclusively, Group III received of PCM and proximol (0.8 mg/kg), Group IV was given V. origena extract at a dosage of 100 mg/kg alone, and Group V received V. origena extract at a dosage of 200 mg/kg alone. In group VI, we received PCM (500 mg/kg) and 100 mg/kg of V. origena extract. Simultaneously, group VII received PCM.. Read More»
  

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