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Advances in Bioengineering and Biomedical Science Research(ABBSR)

ISSN: 2640-4133 | DOI: 10.33140/ABBSR

Impact Factor: 1.7

Ratna Sitompul

Ophthalmology Department, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Indonesia

Publications
  • Research Article   
    Biosafety of Polymethyl Methacrylate as Glaucoma Drainage Plate
    Author(s): Virna Dwi Oktariana Asrory*, Bambang Soegijono, Ratna Sitompul, Widya Artini and William H. Morgan

    This study assesses surface roughness, biomaterial alteration and chemical compound on the polymethylmethacrylate plate of glaucoma drainage device (GDD) pre and 30 days post implantation on rabbit’s eye. The implant’s surface roughness was examined in 2D and 3D by Atomic Force Microscopy (AFM). The biomaterial alteration was assessed by Fourier Transform Infrared Spectroscopy (FTIR). Any tissue adhesion was also assessed since it might affect the result of the examination. Chemical compound was measured by Gas Chromatography Mass Spectrometry (GCMS). In the preimplantation assessment of surface contour, there were some sloping and rising area, but the range of amplitudo was around 28 nm. The feature of the implant in 2D was quite smooth. There were slight roughness changes of the PMMA plate after implantation and the range of amplitudo became around 22.9 nm. The elevation.. Read More»

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