Journal of Pathology and Laboratory Medicine(JPLM)

Torrance Memorial Medical Center, Department of Pathology, 3330 Lomita Boulevard, Torrance, CA 90505, USA

Publications

• Research Article   
  Long Covid and Neurodegenerative Disease
  Author(s): Patrick Chambers*
  
  Brain fog with compromised ability to concentrate has been the most frequent Long Covid (LC) complaint. This is due to an increased TGF beta/IFN gamma with consequently increased bradykinin (BKN), especially in Caucasian females. Brain and lung blood vessels “leak.” This same ratio is increased in Alzheimer’s disease (AD), but decreased in Parkin- son’s disease (PD), because CD4+ and CD8+ T cells are differentially affected by the invading associated viruses, e.g., SARS CoV2, HIV, Varicella zoster (VZV).... In Covid-19 CD147 receptors on immune cells are critical in generating the increased TGF beta/IFN gamma and those on endothelial cells, platelets, and erythrocytes are critical to the abnormal microvascular blood flow. ACE2 receptors on pneumocytes and enterocytes enable pulmonary and GI entry, initiating gut dysbiosis. Epigenetics, methylation, magnesium, v.. Read More»
  

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