Advancements in Journal of Urology and Nephrology(AJUN)

Department of Anatomy, Physiology and Genetics, Uniformed Services University, Bethesda, MD, United States

Publications

• Research Article   
  Liver Function Enzymes are Potential Predictive Markers for Kidney Allograft Dysfunction
  Author(s): Alakesh Bera, Eric Russ, Rahul M Jindal*, Maura A Watson, Ofer Eidelman, John Karaian, Harvey B Pollard and Meera Srivastava*
  
  Introduction: Biopsy of the allograft is the gold standard for assessing kidney allograft dysfunction. The aim of our pilot study was to identify serum biomarkers that could obviate the need for biopsy. Materials and Methods: We conducted a study to identify the biomarkers in the serum from different groups of chronic kidney disease (CKD) patients and kidney transplanted patients vs. healthy individuals. The four groups (n=25 in each group) were as follows: 1) Patients with unstable kidney allograft transplants requiring biopsy for cause, 2) Patients with stable kidney allograft transplants, 3) Patients with CKD not on immunosuppressive therapy and, 4) healthy subjects. We measured the activity and level of serum alkaline phosphatase (ALP) and other liver enzymes (alanine transaminase (ALT) and aspartate transaminase (AST)) as potential seru.. Read More»
  

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