Toxicology and Applied Pharmacology Insights(TAPI)

Department of Pharmacology, School of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Publications

• Research Article   
  Licorice (Glyccyrhiza Glabra) Accelerates the Burn Wound Healing in Rats and Inhibits Growth of Skin Pathogens In-Vitro
  Author(s): Mohsen Zabihi*, Pooya Taherifard, Ali Mohammad Ranjbar and Fatemeh Shishehbor
  
  Background: Skin heat damage is considered as one of the most devastating condition and may cause some morbidities and mortalities. Licorice (Glycyrrhiza glabra) is used in traditional Iranian medicine to treat burns. Methods: Second- and third-degree burns on the dorsal skin in rats were induced under general anesthesia by a metal plate (2 cm in diameter). The wounds were treated topically with 6 concentrations of licorice root hydroalcoholic extract, silver sulfadiazine cream (1%) or normal saline as control for 21 days. Subsequently, the macroscopic and the histopathologic parameters including epithelialization, neutrophil migration, angiogenesis, collagen formation and wound contraction were evaluated. The anti-bacterial effects of the extract on some pathogens of wound infections including Staphylococcus aureus, Pseudomonas aeruginosa a.. Read More»
  

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