Journal of Gastroenterology & Digestive Systems(JGDS)

Internal medicine, East Tennessee State University, Johnson City, TN, USA

Publications

• Review Article   
  Current Evidence On GLP-1 Receptor Agonists: Impact On Residual Gastric Content and Endoscopy Quality
  Author(s): McKenna Andrews*, Hezborn Magacha, David Berry, Sagar Nagpal, Mark F Young and Venkata Vedantam
  
  Glucagon-like peptide-1 (GLP-1) receptor agonists, introduced in 2005, have become crucial in managing type 2 diabetes mellitus (T2DM) by regulating gastrointestinal motility and metabolic disorders. These agents, including exenatide and liraglutide, effectively lower HbA1c levels, reduce body weight, and minimize hypoglycemia risk by mimicking the endogenous incretin hormone GLP-1. GLP-1 receptor agonists enhance insulin secretion, inhibit glucagon release, and promote satiety, which aids in glucose homeostasis and weight management. Additionally, these agonists provide cardiovascular benefits, reducing the risk of major adverse cardiovascular events in T2DM patients. The primary mechanism of action involves delaying gastric emptying by modulating smooth muscle contractions and inhibiting gastric secretions, thus helping flatten postprandial glucose spikes and enhance satiety. This d.. Read More»
  

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