International Journal of Probiotics and Dietetics(IJPD)

Department of Medicine and Therapeutics, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR, China

Publications

• Research Article   
  The Effect of a Novel Probiotic Formula (SMT04) in Reducing Colorectal Cancer- Associated Biomarkers
  Author(s): Jessica YL Ching*, Pui Kuan Cheong and Jessie Qiaoyi Liang
  
  Background and aims: Certain probiotic bacteria have been shown to reduce the risk of CRC in animal experiments. This pilot study aimed to determine the efficacy and safety of a novel probiotic formula, SMT04, which consists of Bifidobacterial and Streptococcus, in reducing CRC-associated bacterial pathogens in humans. Methods: This was a pilot study of subjects taking SMT04 for 3 months (50 billion CFU per sachet). Subjects aged 18 or above who underwent colonoscopy within one year were enrolled. Exclusion criteria included a history of CRC; severe co-morbidity; and use of probiotics, prebiotics, or antibiotics within 30 days. Subjects underwent a noninvasive stool test for the quantitation of three CRC-associated bacterial DNA markers (Fn, m3 and Ch) by qPCR according to a prespecified protocol at baseline, month 1, month 2, and month 3. T.. Read More»
  

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