Ijioma Okorie
Department of Human Nutrition and Dietetics, Michael Okpara University of Agriculture Umudike, Nigeria
Publications
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Research Article
Effect of Methanol Extract of Justicia Carnea Leaf on Some Hematological Parameters of Phenylhydrazine-Induced Anaemic Rats
Author(s): Ijioma Okorie*, Elizabeth Ngozi Chukwuemeka, Joy Oguine and Ojinika Confidence Chinyere
Introduction/Objectiv: Anaemia is a major public health concern that can be prevented, and plant-based materials offer a cost-effective approach to prevention. This study investigated the potential benefits of methanol extract of Justicia carnea leaf in preventing anaemia by examining its effects on hematological parameters in rats with phenylhydrazine-induced anaemia. Methods: Experimental study design was used to randomly assign 20 rats with similar weight into 4 groups of 5 rats each. J. carnea extract was performed using standard method. The groups are; Group 1 (300 mg/kg J. carnea extract), Group 2 (500 mg/kg J. carnea), Group 3 (100 mcg/mL fersolate), and Group 4 (no treatment). Rats received various doses of extract and fersolate, concurrently with 50 mg/mL of phenylhydrazine solution. Phytochemical, and micronutrient .. Read More»