Hari Sharan Makaju
Clinical Biochemist, Kathmandu Pathlab & Diagnostic Center, Nepal
Publications
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Research Article
Association of Apolipoprotein B /Apolipoprotein A-I Ratio with Cardio Metabolic Risk Biomarkers in Type 2 Diabetes Mellitus
Author(s): Hari Sharan Makaju, Vijay Kumar Sharma*, Binod Kumar Yadav, Eans Tara Tuladhar, Roshan Bhandari, Aseem Bhattarai, Mithileshwor Raut, Raju Dubey, Apeksha Niraula, Alisha Sapkota, Anant Neupane and Rabina Ramtel
Background: Individuals diagnosed with Type 2 Diabetes Mellitus and metabolic syndrome are at a heightened risk for cardiovascular disease. Apolipoprotein B (Apo B) is a reliable measure for assessing atherogenic particles, while Apolipoprotein A-I (ApoA-I) plays a key role in antiatherogenic high-density lipoproteins. Timely identification and evaluation of cardio metabolic risk factors can decrease the likelihood of developing CVD. Objectives: This study aimed to evaluate the association of Apo B/Apo A-I ratio with cardiometabolic risk biomarkers in T2DM. Materials and Methods: This cross-sectional study conducted at Tribhuvan University Teaching Hospital and involved 120 individuals diagnosed with Type 2 Diabetes Mellitus who visited the Medicine Outpatient Department, as well as 120 apparently healthy controls... Read More»