Advancements in Journal of Urology and Nephrology(AJUN)

Sussex Kidney Unit, University Hospitals Sussex NHS Trust, United Kingdom

Publications

• Research Article   
  MMF as Immunosuppressive Therapy in IgA Nephropathy
  Author(s): Conor Murphy, Henry Barrington-White, Abigail Pomeranc and Farid Ghalli*
  
  Introduction: IgA Nephropathy (IgAN) is the most common cause of primary glomerulonephritis in developed countries. Treatment with ACEI/ARB has strong evidence in managing IgAN. If there is evidence of progression, immunosuppression is recommended. KDIGO guidelines do not advise Mycophenolate Mofetil’s (MMF) use in non-Chinese population currently. Methods: In this study, we reviewed immunosuppression with MMF retrospectively in IgAN patients managed at the Sussex Kidney Unit (SKU) – Brighton – United Kingdom. This was assessed using the primary measures of renal survival without requiring renal replacement therapy (RRT) and proteinuria reduction to >50% of the diagnosis baseline. Twenty-five patients diagnosed with IgAN between 2011 and 2020 and had been treated with MMF were retrospectively reviewed. Data was collected.. Read More»
  

  Abstract HTML PDF