Safaa Mourabit
Department of Internal Medicine and Geriatrics, Ibn Rochd University Hospital Center, , Faculty of Medicine and Pharmacy of Casablanca, Morocco
Publications
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Research Article
Mixed Connective Tissue Disease: A Rare Disease with Many Faces
Author(s): Chaimaa Zeroual*, Afaf Aallam, Safaa Mourabit, Mina Moudatir, Khadija Echchilali and Hassan Elkabli
Introduction: Mixed connective tissue disease (MCTD) is a rare autoimmune disease characterized by overlapping clinical manifestations of several systemic connective tissue diseases and the presence of anti-U1RNP antibodies. This study aims to describe the clinical, immunological, and evolutionary features of patients with MCTD. Methods: A retrospective descriptive study conducted over 5 years (2020–2024) in the internal medicine department of Ibn Rochd University Hospital Center in Casablanca, including 9 female patients meeting Kasukawa’s criteria. Results: All patients were female, with a mean age at diagnosis of 41.3 years. Raynaud’s phenomenon was the most frequent inaugural sign. Pulmonary involvement was present in 66.6% of cases, with one-third of these patients exhibiting fibrotic changes.. Read More»

