Advances in Bioengineering and Biomedical Science Research(ABBSR)
ISSN: 2640-4133 | DOI: 10.33140/ABBSR
Impact Factor: 1.7
Rufina Soomro
Prof. of Surgery & Consultant Breast Surgeon, Liaquat National Hospital & Medical College, Karachi, Pakistan
Publications
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Research Article
Correlation of OncotypeDx Recurrence Score, Nottingham Prognostic Index, and Ki67
Author(s): Rufina Soomro*, Azmina valimohd, Naila zahid, Najeeb Naimatullah and Noureen Durrani
Objective: To identify the correlation between the OncotypeDx Recurrence score, Nottingham Prognostic Index (NPI), and Ki67. Material & Methods: A retrospective study was conducted at Liaquat National Hospital where medical records of early-stage breast cancer patients, who had OncotypeDx RS done were reviewed from 2008-2019. The patient’s age, Histopathology type, tumor grade, size, No. of nodes involved, ER, PR, Her neu and Ki67 were collected. OncotypeDx RS, NPI, and Ki67 were categorized into 3 groups and statistical analysis was done to find a correlation between OncotypeDx RS, NPI and Ki67. Result: Total 76 patient’s records were reviewed. The average age of study participants was 56.40 ± 10.32 years. Oncotype-Dx method categorized 34 (44.74%), 26 (34.21%) and 16 (21.05%) patients as low, moderate and high ri.. Read More»