Advancements in Journal of Urology and Nephrology(AJUN)
ISSN: 2689-8616 | DOI: 10.33140/AJUN
Impact Factor: 1.0
Otokpa DE
Department of Medicine (Renal Unit) University of Calabar Teaching Hospital Calabar, Nigeria
Publications
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Research Article
Decaffeinated Coffee Consumption and Renal Function Impairment in Health and Diabetes: A Paradigm-Shift
Author(s): Ekpenyong, CE*, Nwachuku C and Otokpa DE
Aim: The belief that decaffeinated coffee (DCAF) does not contain a physiologically relevant concentration of caffeine and therefore has no significant adverse effect on renal endpoints makes patients who are vulnerable to renal dysfunction, renal compromised state, medical conditions that contraindicate caffeine intake or those already on prescription medications known to adversely affect the kidney to sometimes substitute DCAF for caffeinated coffee even as the credibility of this paradigm remains disputable. Therefore, the present study aimed to assess the effect of DCAF consumption on markers of renal function and carbohydrate metabolism in health and diabetes. Materials and Methods: Sixty Wistar Albino rats were divided into 12 groups (6pairs) (n=5per group) for male and female animals. Animals in group 1 served as normal control (NCTRL.. Read More»