Toxicology and Applied Pharmacology Insights(TAPI)
ISSN: 2641-0451 | DOI: 10.33140/TAPI
Ode Julius Okwoche
Department of Pharmacology Toxicology, Faculty of Veterinary Medicine, University of Abuja, Nigeria
Publications
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Research Article
Evaluation of Aqueous Methanol Stem Bark Extract of Stereospermum kunthianum (pink jacaranda) for Wound Healing Effects in Alloxan-induced Diabetic Rats
Author(s): Ifeadi Chekwube Nkemjika*, Nwinyi Florence Chimezie, Ode Julius Okwoche, Ramon-Yusuf Suleiman Babatunde and Onah Jonas Anayo
Background and Purpose: The stem bark of Stereospermum kunthianum is used extensively in traditional medicine to treat wounds, inflammatory and other pain related health conditions in humans. The aim of this study was to evaluate the wound healing properties of the stem bark extract of S. kunthianum in alloxan-induced diabetic rats. Experimental Approach: The aqueous methanol extract of S. kunthianum was analysed for phytochemical constituents, acute toxicity tests in rats. The stem bark extract of S. kunthianum was evaluated for wound healing using excision and incision wound healing models in diabetic rats. Results: The aqueous methanol extract of S. kunthianum revealed that saponins, terpenes, tannins and steroids were present. The acute toxicity study in rats up to 72 hrs. Showed no observed toxicity sign up to.. Read More»