International Internal Medicine Journal(IIMJ)
ISSN: 2837-4835 | DOI: 10.33140/IIMJ
Impact Factor: 1.02
Nakavuma Anitah
Department of Medical Laboratory Science, Faculty of Medicine, Mbarara, University of Science and Technology P.O BOX, 1410, Mbarara City, Uganda
Publications
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Research Article
HRP2 and PLDH Performance Comparison as Rapid Diagnostic Tools for Symptomatic Malaria Patients at Rugazi HC IV in Rubirizi District
Author(s): Nakavuma Anitah*, Musau Immanuel Afrika, Lumu Hassan, Atimaaku Palma Rose, Ankunda Evalyne, Agaba Bosco, Okongo Benson, Kalyetsi Rogers, Ssendyabane Frank, Muwanguzi Enock, Charles Nkubi Bagenda and Simon Peter Rugera
Background: Rapid and precise laboratory diagnosis is essential for effectively diagnosing and managing malaria patients. Malaria rapid diagnostic tests (mRDTs) play a critical role in malaria diagnosis in resource-constrained settings with limited access to labs and trained staff. The efficiency of two mRDTs (HRP2 and pLDH) was compared against microscopy, the gold standard for malaria diagnosis, in this study. Methods: In a cross-sectional study, 308 participants were tested for malaria parasites using two mRDTs and blood smear microscopy as the gold standard. STATA software version 17 was used for data analysis. Results: Out of the 308 participants, 82 tested positive for HRP2 mRDT (26.62% (95% CI: 21.97-31.86) positivity rate, 73.38% (95% CI: 68.14-78.83) negativity rate), and 99 tested positive for pLDH mRDT (.. Read More»