International Journal of Women's Health Care(IJWHC)
ISSN: 2573-9506 | DOI: 10.33140/IJWHC
Impact Factor: 1.011
M.McCormack
Clinical Oncology, University College London Hospital UCLH NHS Foundation Trust, London, UK
Publications
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Research Article
Uterine Carcinosarcoma: A Single Centre Retrospective Clinical Cohort Analysis
Author(s): C Perna*, G Eminowicz, U Asghar, G Imseeh, AA Kirkwood, A Mitra, R Kristeleit and M.McCormack
Objective: Carcinosarcomas are rare, heterogeneous tumours with a poor prognosis and no well-defined treatment pathway. Through analysis of a cohort of University College London Hospital (UCLH) patients, we assessed potential known clinicopathological prognostic factors by looking at the association of baseline characteristics with progression free survival (PFS) and overall survival (OS). Methods: Women with uterine carcinosarcoma treated at UCLH from 2003 to 2014 were retrospectively identified and analysed. Clinicopathological data and treatment history were collected from patient records. Results: 73 patients were included. 69.9% were FIGO stage I/II, 62.2% had heterologous elements and 60.0% had lymphovascular space invasion (LVSI). Adjuvant chemotherapy and radiotherapy (RT) was received by 48% of patients, 2.. Read More»