Dermatology Journal of Cosmetic and Laser Therapy(DJCLT)

Cantabria Labs Difa Cooper Medical Department, Caronno Pertusella (VA), Via Milano 160;, Italy

Publications

• Review Article   
  The Rational of a Fixed Combination of Benzoyl Peroxide and Niacinamide in the Treatment of Acne Vulgaris: A Narrative Review
  Author(s): Massimo Milani* and Francesca Colombo
  
  Acne vulgaris (AV) in a common skin disease affecting mainly adolescents but could be present also in adult subjects. AV is characterized by the presence of non-inflammatory (comedons) and inflammatory (papules, pustules, cysts, and nodules) lesions affecting sebaceous glands rich regions like the face, back, shoulder and thorax. A central pathogenetic role of AV lesions seems played by Cutibacterium acnes, especially some phylotypes (i.e. C. acne IA1) able to induce an inflammatory response at the level of sebaceous glands. Other important pathogenetic factors of AV are the androgen-driven increase of sebum production and the process of hyperkeratinisation of the infundibulum. The first line treatment of AV is in general done using monotherapy with antibacterial agents like benzoyl peroxide (BPO) and hydrogen peroxide or topical retinoid mole- cules. These two classes of drugs could .. Read More»
  

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