Majid Zandkarimi
Faculty of pharmacy, Department of pharma- ceutics, Azad university of Medical Sciences, Tehran, Iran
Publications
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Research Article
Effect of Trachyspermum Ammi (Ajwain) Fruit's Aqueous Extract on Atropine Induced Dry Eye in Male Mice
Author(s): Ayda Chavoshi Aghdam*, Majid Zandkarimi and Mahsa Hadipour Jahromy
Dry eye syndrome (DES) is a common eye disorder that is described as a tear film disorder caused by reduced tear production, poor tear quality, or excessive tear evaporation. This disorder is associated with symptoms of eye discomfort such as irritation, foreign body sensation, redness and itching. This disease affects the lives of millions of people and its prevalence reaches 14.5%, which is still increasing. Many evidences indicate that the increase in tear film osmolality and ocular surface inflammation caused by T cells play a role in the pathogenesis of the disease. However, the exact pathogenesis of DES is not fully understood. Oxidative stress has recently been found to play a prominent role in the development of dry eye. Purpose of study: To investigate the therapeutic effects of topical administration of the aqueous extract of the fruit of the .. Read More»