Journal of Veterinary Health Science(JVHS)

Department of Health and Health Care Administration, Swami Rama Himalayan University (SRHU), Dehradu, India

Publications

• Research Article   
  Evaluation of Biochemical, Hematological and Oxidative Parameters in Mice Exposed To the Binapacryl
  Author(s): Kehinde S*, Adebayo S. M, Kade E. A, Adesiyan A. L and Gurpreet K
  
  We evaluated the toxicity of hepatic, hematological, and oxidative effects of binapacryl on female albino mice. The animals were treated orally with 50, 100, 150 and 200 mg/kg body weight of the binapacryl, on a daily basis for a period of 15 days. Distilled water was used as control treatment. Samples of blood and hepatic tissue were collected at the end of the treatment. Hepatotoxicity was monitored by quantitative analysis of the serum enzymes ALT, AST, γ-GT, urea and creatinine. We also investigated liver tissues histopathologically. Alterations of hematological parameters were monitored by RBC, WBC, hemoglobin, hematocrit, MCV, MCH, and MCHC. Significant increases in the levels of hepatic enzymes (ALT, AST, and γ-GT) were observed for both binapacryl treatments, but no considerable differences were found by histological analysis. The hematological parameters showed si.. Read More»
  

  Abstract HTML PDF