Advances in Bioengineering and Biomedical Science Research(ABBSR)

President of European Bio Immune(G)ene Medicine Association (EBMA), Internal medicine practice, Germany

Publications

• Research Article   
  Bio Immune(G)ene Medicine and the Use of miRNAs to Regulate the Cell
  Author(s): Maria Carme Pares Santilari and Gilbert Glady*
  
  MicroRNAs (miRNAs or miRs) are a type of non-coding RNA molecules that regulate the gene expression in a negative way, by downregulating the gene expression mainly at the post-transcriptional level, either by the mRNA degradation process or the inhibition of the translation. The role that many miRNAs play in the pathogenesis of several diseases is well known, such as in the inflammation process, in several steps of the oncogenesis or the metabolism of several virus and bacteria among many others. One of the main limitations in the therapeutic use of miRNAs is the ability to reach the target, as well as doing so without causing any collateral damage. One microRNA can indeed regulate up to 200 target-genes, and one gene can be influenced by a lot of different microRNAs. This is the purpose of the Bio Immune(G)ene Medicine: to achieve the cell without harm, use all the molecular resource.. Read More»
  

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