El-Sayed A. Abd El-Mabood
Department of General & Vascular Surgery, Benha University, Egypt
Publications
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Research Article
Treatment of Acute Iliofemoral Deep Vein Thrombosis: Does Catheter Directed Thrombolytic Therapy Change Outcomes
Author(s): Ayman M. Fakhry*, El-Sayed A. Abd El-Mabood, Waleed A. Sorour, Ayman M. Abdelmofeed, Ahmed Fouad Ahmed, Mohamed E. Abd Ellatief and Saied ELMOKKADEM
Background: Iliofemoral deep vein thrombosis (DVT) is associated with severe post-thrombotic morbidity when treated with anticoagulation alone. Catheter- directed thrombolysis (CDT) allows early removal of thrombus and reduces valvular reflux and Post-thrombotic Syndrome (PTS). Patients and methods: This prospective randomized multi-center controlled two- arm blind study was conducted in 6 centers on 252 patients with iliofemoral DVT. Patients were randomly allocated by using simple random allocation cards method into two groups; Group (A): CDT followed by oral anticoagulation (N=126 (50%)), Group (B): Standard DVT therapy (N=126 (50%)). Follow-up was for 24 months. Results: Patients of group (A) significantly complained less pain at 10 & 30 days (P-Value: 0.02 & 0.04 respectively). Also there was significa.. Read More»