Journal of Pathology and Laboratory Medicine(JPLM)
Dr. Dayal Singh Bisht
Assistant Professor, Department of Pathology, MM collage of medical Sciences & research, Ambala, Har, India
Publications
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Research Article
To Compare the Manual Liquid-Based Cytology (MLBC) Technique on Fine-Needle Aspiration Cytology (FNAC) Material with Conventional Technique
Author(s): Dr. Dayal Singh Bisht*, Dr. Sanjyokta and Dr. Sandhya Panjeta Gulia
Liquid Based Cytology (LBC) is a monolayer slide preparation technology that has outperformed conventional pap smears due to improved fixation, reduced masking factors and standardised cell transfer. In LBC, samples are collected by total immersion of the sampling apparatus in a vial containing a preservative solution, with cells being preserved and fixed at the same time, as opposed to conventional smears where the sample is sprayed onto a glass slide and fixed separately. Two main liquid preparation methods are currently known - ThinPrep and SurePath. In our study we used MLBC in fine-needle aspiration cytology (FNAC). It aimed to observe morphological characteristics, compare the outcomes of direct smear examinations with those of manual liquid-based smears, and correlate these findings with histopathological results in cases where a biopsy was also performed. AIM.. Read More»