Advances in Bioengineering and Biomedical Science Research(ABBSR)
ISSN: 2640-4133 | DOI: 10.33140/ABBSR
Impact Factor: 1.7
Daniele Scalisi
Azienda Ospedaliera Universitaria Policlinico, Fisica Sanitaria, Palermo, Italy
Publications
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Research Article
The Role of Radium 223 Planar Whole-Body Scan in the Management of Patients with Bone Metastates
Author(s): Renato Patrizio Costa*, Vincenzo Tripoli, Alessandro Princiotta, Alessandra Murabito, Maria Licari, Fabio Trombetta, Daniele Scalisi and Antonio Pinto
The multidisciplinary treatment with targeted alpha therapy, as the treatment with Radium 223, plays an important role in the management of patients with castration resistance prostate cancer and metastatic bone disease. The AUA approved the Ra223 as the second line of treatment of castration resistance prostate cancer in patients with bone metastases, in the absence of visceral metastases. Currently the EMA authorizes the use of Ra223 at a dose of 55 kBq / kg for a total of 6 administrations in patients with CRPC, but the dose of Ra223 needs to be made on an individual patient basis taking into consideration the potential clinical benefits and risk. We have outlined a new methodology, which can be executed in all departments of nuclear medicine in collaboration with health-related physics at no cost. Our methodology allows a correct evaluation of the doses of Radium 223 to .. Read More»