International Journal of Nanotechnology and Nanomedicine(IJNN)
ISSN: 2476-2334 | DOI: 10.33140/IJNN
Impact Factor: 0.836
Benjamin Ray
University of Utah College of Health, Salt Lake City, UT, USA
Publications
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Research Article
Advances in Nanocarrier Systems for Dermatologic Transdermal Drug Delivery: A Chemical and Molecular Review
Author(s): Andres D Parga* and Benjamin Ray
Background: Transdermal drug delivery faces significant barriers due to the physicochemical properties of the stratum corneum, limiting the passive diffusion of therapeutic agents. Nanocarrier systems, including liposomes, ethosomes, niosomes, and polymeric nanoparticles, are being extensively investigated as innovative platforms to overcome these limitations in dermatologic applications. Objective: This review synthesizes recent advances in the molecular design of nanocarrier systems engineered for enhanced transdermal drug delivery, emphasizing critical chemical principles that underpin their development and optimization. Methods/Discussion: A targeted literature review was conducted using PubMed, Scopus, and Web of Science databases, identifying studies published between January 2023 and April 2025. A total of 6.. Read More»