Journal of Veterinary Health Science(JVHS)

National Animal Health Diagnostic and Investigation Center, Sebeta, Ethiopia

Publications

• Review Article   
  The Role of Type IV Secretion System in Brucella Virulence: A Review
  Author(s): Bayeta Senbeta Wakjira*
  
  Brucellosis is a bacterial disease of domestic and wild animals caused by the genus Brucella which has great public health importance globally. In general, Brucella species do not express toxins or virulence factors that cause direct damage to the host. Instead, this pathogen’s strategy is to persist long enough in the infected host until transmission can occur, which in the natural hosts is usually through abortion, sexual contact, or shedding of bacteria in milk. One important Brucellavirulence factor for intracellular survival and persistence in the host is the type IV secretion system (T4SS).The type IV secretion system (T4SS) is one of numerous secretion systems used by microbes to transfer macromolecules through the cell membrane, such as proteins and DNA. It’s the most versatile secretion system, transporting monomeric proteins, multi-subunit protein poisons, and nu.. Read More»
  

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