Journal of Veterinary Health Science(JVHS)
ISSN: 2831-3887 | DOI: 10.33140/JVHS
Impact Factor: 0.762
Basudha Khanal
Professor, Department of Microbiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal
Publications
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Research Article
Invitro Activity of Tigecycline against Multidrug-Resistant Enterobacteriaceae from Blood Stream Infection in a Tertiary Care Hospital of Nepal
Author(s): Yadav*, Basudha Khanal and Narayan Raj Bhattarai
Background: Multidrug resistant (MDR) enterobacteriaceae like extended spectrum beta lactamase (ESBL) and metallo-beta lactamase (MBL) are being encountered as the causative agents of blood stream infection. To overcome this, accurate diagnosis of MDR pattern with appropriate antibiotics is required. Tigecycline is a broad spectrum antibiotic which exhibit strong activity against MDR enterobacteriaceae. This study is aimed to find out resistance pattern like ESBL and MBL with invitro activity of tigecycline against enterobacteriaceae. Methods: A descriptive cross-sectional study was conducted in the Department of Microbiology, B.P. Koirala Institute of Health Sciences, from 1st September 2014 to 31st August 2015. Confirmation for ESBL was done as recommended by Clinical and Laboratory Standard Institute (CLSI) and MBL production was detected.. Read More»