Aurangzeb Pirzada
UK
Publications
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Review Article
A Review of the Involvement of Disturbed Treg/CTC Ratios in the Sustained Proliferation of Psoriasis with a Brief Gender Distribution Analysis
Author(s): Aurangzeb Pirzada
Aim: To provide evidence from current literature that psoriasis is an autoimmune disorder involving a highly proliferated effector response in relation to a suppressed, inactivated and outnumbered regulatory component. Disease Background Pathophysiology: Discusses the octet phenotypes, histological analyses, epidemiological data, additional components followed by briefly reflecting on its psychoanalytical aspects. Evidence Based Review: Provides a historical perspective of Treg research and spans Treg details across cellular, molecular and genetic details mentioning its subtypes, TCR signalling comparison and marker diversity moving onto bringing FOXP3 under spotlight to discuss its structure, pathways followed by establishing a link between Treg and psoriasis. Materials and Methods: Discusses laboratory technique.. Read More»
