Adity Bose
Department of Chemistry, Presidency University, 86/1 College Street, Kolkata 700073, West Bengal, India
Publications
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Research Article
Evaluation of Sinapic Acid to Ameliorate Ionizing Radiation Induced Peripheral Blood Mononuclear Cell Death
Author(s): Prasenjit Mondal, Adity Bose and Sarmishtha Chanda
Introduction: The UV radiation is known as a potential environmental carcinogen which causes damages of macromolecules like DNA, RNA, lipid, and protein inside the cell and eventually causes cell death. Persons who chronically exposed to UV radiation due to occupational or environmental exposure have a potential risk to develop cancer of the skin and internal organs. Polyphenols have a promising role in scavenging reactive oxygen species developed in our body due to a variety of exposure including radiation. In the present study, we are therefore evaluating the role of sinapic acid (SA), a polyphenol, in scavenging UV radiation-induced generation of reactive oxygen species and eventual cell death. We have studied the biological activity of SA as a potential antioxidant on human peripheral blood mononuclear cells taken from human volunteers. Methods.. Read More»