Aanuoluwa J Salemcity
Department of Biochemistry, Faculty of Basic Medical Sciences, University of Medical Sciences, Ondo, Ondo State, Nigeria
Publications
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Research Article
Investigating the behavioral and antioxidative effects of ethanolic extract from Schumanniophyton magnificum (K. Schum) in ketamine-induced psychosis in mice
Author(s): Ayomide G Olusola, Abiola M Asowata-Ayodele*, Olalekan Olatuyi, Felix Afolabi, Aanuoluwa J Salemcity and Babawale Peter Olatunji
This study investigates the behavioral and antioxidative effects of ethanolic extract from Schumanniophyton magnificum (K. Schum) in a mouse model. Psychosis poses significant health risks globally, influencing various aspects of mental and physical well-being, such as impaired reasoning, depression, memory loss, and social isolation. Despite its relevance, there is a lack of research into the potential therapeutic effects of Schumanniophyton magnificum leaves in managing psychosis, underscoring the need for innovative treatment approaches. In this study, Schumanniophyton magnificum was administered orally to groups of ketamine-induced psychotic mice at dosages of 100, 200, and 400 mg/kg for 14 days, with a control group for comparison. Behavioral assessments were conducted using the Open Field Test to measure hyperlocomotion, the Y-Maze Test to evaluate learning and memory (cognition.. Read More»

