Journal of Pathology and Laboratory Medicine(JPLM)
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Maraud and Gizzard-Hepatosplenic T cell Lymphoma
Abstract
Anubha Bajaji
Hepatosplenic T cell lymphoma is an exceptionally discerned, aggressive, extra-nodal lymphoma engendered from non activated, cytotoxic T lymphocytes which pre-eminently exemplify T cell receptor gamma/delta (TCRγδ). Hepatic parenchyma and bone marrow delineates a sinusoidal pattern of malignant T cell infiltration. Besides, quantifiable clonal T cells and abnormal T cells appear elevated within hepatic parenchyma, bone marrow, spleen or occasionally within peripheral blood.