Green Synthesis, Characterization and Biological Evaluation of Barium Oxide Nanoparticles Using Mirabilis Jalapa L. Stem Extract

Abstract

Abbas Khan*, Aftab Alam, Zakir Khan, Sheema Bibi, Sha Fahad, Hamania Yousaf, Warisha Malik and Alisha Kanwal

This paper presents a synthesis of BaO nanoparticles by utilizing the stem extract of Mirabilis Jalapa L. Only BaCl2 and Na2CO3 were employed as precursors. For the determination of structural and morphological properties, the fresh greenly prepared barium oxide nanoparticles were characterized by using various characterization techniques. Sharp and narrow peaks in the XRD spectrum indicate the pure and crystalline nature (crystallite size>50nm) of as-synthesized BaO-NPs. Morphology of BaO- NPs was studied via SEM according to which Greenly synthesized BaO-NPs of spherical and relatively irregular flower-like shape with a diameter range 20-40 nm. The MABA method and the Agar Tube Dilution method were used for antibacterial and antifungal assays. The BaO-NPs presented substantial antibacterial activity against Escherichia coli (78%) and Pseudomonas aeruginosa (60%) along with broad antifungal activity, notably against Microsporum canis (91%). This study highlights a simple, eco-friendly, cost-effective synthesis route and the biomedical potential of plant-mediated BaO-NPs.

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