International Journal of Clinical and Medical Education Research(IJCMER)

Sri Ramachandra Institute of Higher Education and Research Porur, India

Publications

• Research Article   
  Evaluation of Metabolic Changes and Treatment Outcomes Associated with Risperidone in Paediatric Patients
  Author(s): Karthik Thiyagarajan, Paul Lessel, Sindhu Selvam* and Udayakumar Narasimhan
  
  Risperidone is widely used in treating pediatric neuropsychiatric disorders but concerns about its metabolic side effects—especially weight gain—remain significant. This prospective observational study was conducted in a tertiary- care hospital to evaluate short-term metabolic changes and behavioral outcomes in children aged 7 to 12 years who were newly initiated on risperidone. A total of 27 antipsychotic-naïve children were followed for an average of 9.5 weeks. Baseline and follow-up assessments included anthropometric measurements, fasting laboratory tests, and behavioral evaluation using the Child Behavior Checklist (CBCL). Over the study period, children showed a significant mean weight increase of 3.59 kg, and a BMI increase of 2.21 kg/m2—reflecting more than a 12% rise in both parameters. The degree of weight and BMI gain showed moderate correlation with .. Read More»
  

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