Advancements in Journal of Urology and Nephrology(AJUN)
ISSN: 2689-8616 | DOI: 10.33140/AJUN
Impact Factor: 1.0
Tolulope F Okanlawon
Department of Chemical, Federal Institute of Industrial Research, Nigeria
Publications
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Research Article
Diuretic and Anti-Hypertensive Activity of Clerodendrum Chinense (OSBECK) MABB. Aqueous Extract in 8% Salt Diet-Induced Hypertensive Rats
Author(s): Joy I Odimegwu*, Tolulope F Okanlawon, Oluwakayode Ezekiel Olatunji and Ishola Ismail
Diuresis refers to an increase in the rate of urine flow and sodium excretion from the system via the urine. It is a necessary excretory process that may prove difficult for some disease systems e.g. enlarged prostates. Hypertension occurs as a result of systolic blood pressure higher than 140 mmHg or a diastolic blood pressure higher than 90 mmHg. It is one of the most common chronic diseases affecting more than a billion people worldwide. A high dietary sodium intake is one of the factors associated with the development of hypertension. Clerodendrum chinensis is used by local communities in West Africa for its diuretic and anti-hypertensive properties. We analyze the phytochemical properties of the mixed leaf, root, and stem aqueous extract of the plant and investigate its anti-hypertensive and diuretic activity in Sodium chloride diet-induced hypertensive rats. The anti-hypertensiv.. Read More»