Shanshan Yang
Department of Neurology, the First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, and, China
Publications
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Research Article
Using Thrombin Time to Evaluate the Efficacy of Anticoagulant Therapy for Acute Cerebral Infarction
Author(s): Qianqian Li, Tingjiao Liu, Yan Gao, Xinxin Guo, Ying Jia, Qian Shi and Shanshan Yang*
Background: Although intravenous thrombolysis therapy considered as a significant progress in the treatment of acute ischemic stroke, there are limited effective treatments for patients with onset ischemic symptom that beyond six hours during acute ischemic stroke. In this study, we investigated the effectiveness of the intravenous argatroban therapy in acute ischemic stroke patients who cannot be treat with intravenous thrombolysis due to the limited time window. Methods: One hundred and eighty patients with acute ischemic stroke that had beyond six hours ischemic symptom were admit to our hospital and analyzed retrospectively. ELISA measured levels of activated partial thromboplastin time (aPTT), prothrombin time (PT) and thrombin time (TT) in peripheral blood of these patients at 24 hours post initial therapy. Results:.. Read More»