Archives of Biology & Life Sciences(ABLS)

Department of Pharmacy, Gopalganj Science and Technology University, Gopalganj-8105, Bangladesh

Publications

• Short Communication   
  A Short Communication on Metastatic Cancer Stem Cells
  Author(s): Md. Takdir Hossain*
  
  Metastatic cancer remains the leading cause of cancer-related mortality and is increasingly associated with a subpopulation of cancer stem cells (CSCs). These cells exhibit self-renewal capacity, tumor initiation potential, and the ability to generate intratumoral heterogeneity. Emerging evidence suggests that metastatic dissemination and colonization may be driven by CSCs capable of surviving systemic spread and adapting to distant microenvironments. Although the CSC model provides a useful framework for explaining tumor recurrence and therapeutic resistance, its universality across cancer types remains debated. Key signaling pathways, including WNT/β-catenin, NOTCH, Hedgehog, BMI1, and EZH2, are implicated in CSC maintenance and metastatic behavior. In addition, epithelial–mesenchymal transition (EMT) and pre-metastatic niche formation further support the link between ste.. Read More»
  

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