Journal of Ophthalmology & Clinical Research(JOCR)

President/CEO, EyeMisra.org, USA

Publications

• Review Article   
  Hypertrophy of the Eye Focusing Ciliary Muscle in Glaucoma and Beneficial Effect of Nitric Oxide
  Author(s): Karan R Aggarwala*
  
  Biophysical and biochemical factors influence progression of myopia and glaucoma. Such factors include degree and du- ration of controlled eye focusing, and metabolism that sustains muscular contraction. Autonomic innervations regulate contractile tissue, adjusting the rate of aqueous outflow. Individual variations are compounded by instrument and exam- iner factors, all of which alter repeatability of measured intra-ocular pressure. Drainage of aqueous humor via the al- ternate, uveo-scleral pathway appears to be amenable to agents such as nitric oxide. The modality by which nitric oxide exerts a beneficial effect is by increasing inter-fiber spacing within the ciliary muscle, reducing density, so aqueous can leave the anterior chamber and permeate into venous circulation. It is hoped that future case-control clinical research studies shall deploy dietary and topical agents to reduce.. Read More»
  

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