Advances in Bioengineering and Biomedical Science Research(ABBSR)

Research Assistant, Department of Human Physiology, School of Laboratory Medicine and Medical Scienc, South Africa

Publications

• Research Article   
  Isolation and Quantification of Nanovesicles in Isoproterenol-Induced Myocardial Infarcted Rats
  Author(s): Aviwe Ntsethe*, Irene Mackraj, Saravanakumar Murugesan and Arunagiri Pandiyan
  
  Introduction and Aim: Myocardial infarction (MI) is one of the leading causes of death worldwide. The pathogenesis and aetiology of MI is still unclear and there is currently no cure for MI. Cardiac troponin is the only well-known cardiac-specific marker for the diagnosis of MI but due to the delayed release of troponin in the circulation, a novel cardiac biomarker is needed in the early stages of development of MI to reduce MI mortality. Recently, it has been reported that exosome concentration is highly regulated by stress and cardiovascular diseases (CVDs). We assessed the hypothesis that exosome secretion by the injured cardiomyocytes is increased during MI and thereby serve as biomarker for MI. The aim of this study was to quantify exosomes in an isoproterenol (ISO)-induced MI rats. Method: Twelve rats were divided into two groups (group A.. Read More»
  

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