Fu Beijing
Mudanjiang Medical University, Mudanjiang 157000, Heilongjiang, China
Publications
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Review Article
Research Progress on the Relationship between Lipoprotein Associated Phospholipase A2 and Coronary Atherosclerotic Heart Disease
Author(s): Zhang Xianmeng, Gao Fengmin*, Zhang Fuya, Fu Beijing and Wen Xin
Coronary atherosclerotic heart disease is a common disease which seriously endangers human health. The incidence rate is increasing year by year and the age of onset is becoming younger. As a kind of Inflammatory factors of vascular, Lipoprotein associated Phospholipase A2 (Lp-PLA2) can promote the progress of inflammation and coronary atherosclerosis, and its serum level can reflect the stability of atherosclerotic plaque. Among the risk factors of coronary heart disease, Lp-PLA2, as a supplement to the traditional risk factors, has a significant reference value for the prediction of coronary heart disease. More and more studies have found that Lp-PLA2 has a significant potential value in evaluating the prognosis of coronary heart disease, especially in acute coronary syndrome patients. This review summarizes the research progress of Lp-PLA2 on the pathogenesis, detection methods, in.. Read More»