Journal of Traditional Medicine & Applications(JTMA)

Harvard University, Boston Children’s Hospital, USA

Publications

• Review Article   
  Cognitive Dysfunction in Parkinson’s Disease: A Traditional Medicine Therapeutic Approach
  Author(s): Ernest Dalle*, Marc O Ondoua Nguele, Herve Narcisse Bayaga and Frederic Melaman Sego
  
  Background: Parkinson’s disease (PD) is an incurable complex neurodegenerative disease pathologically described with a six- stage alpha-synucleinopathy. In stage 4 of the disease, the toxic alpha-synuclein reaches the hippocampus and causes a decline in one or more cognitive abilities, including memory, attention, speech, or visual-spatial ability. Cognitive dysfunction is increasingly recognized among the most important pre-motor symptoms associated with PD, which can severely affect the patient’s quality of life. Furthermore, this pre-motor symptom of PD shares many common pathophysiological mechanisms with oxidative stress, cytotoxicity, or neuro-inflammation in specific individuals. Objective: To highlight the mechanisms of selected traditional medicine therapeutic approaches underlying the prevention and/ or treatment of PD associated with cognitive f.. Read More»
  

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