Charles J. Middleton
Rowan School of Osteopathic Medicine., United States
Publications
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Research Article
Connecting the Dots: Exploring the Interplay of Calcium, Delayed Onset Muscle Soreness, and the Myofascial System
Author(s): Charles J. Middleton*, Gerardo Rivera-Colon, Joseph E. Fares, Seth Spicer and Alexander King
Introduction This study aimed to elucidate calcium's role in muscle fiber inflammation, delayed onset muscle soreness (DOMS), and myofascial remodeling following exercise. The objective was to clarify the etiologies of DOMS in relation to calcium physiology to allow clinicians to modulate its presentation and tissue adaptation more effectively. Methods A review was performed of the current literature regarding the role of calcium in myofascial damage after strenuous exercise. A database search was conducted via PubMed. The types of studies included were randomized controlled trials, crossover studies, double blind studies, retrospective studies, and meta-analysis. Results This study discovered the largest contributor to DOMS is deep fascia damage, which had a higher concentration of nociceptors compared to musc.. Read More»

