Biomedical Science and Clinical Research(BSCR)

Department of Pharmacology and Pharmacy Practice, Maliba Pharmacy College, Uka Tarsadia University, India

Publications

• Case Study   
  Nitrofurantoin-Induced Pulmonary Eosinophilia
  Author(s): Honey Desai*, Sonia Singh and Bhavin Vyas
  
  Nitrofurantoin is an antibiotic used in the treatment and prevention of urinary tract infections (UTIs). However, one serious and rare adverse effect is nitrofurantoin-induced pulmonary eosinophilia (NIPE) - a disease caused by abnormal accumulation of certain white blood cells and Immunoglobulin E (IgE) in the lungs that results in cough, shortness of breath, chest tightness and tiredness. This case report presents a patient who starts experiencing cough, dyspnea, and fatigue after taking nitrofurantoin for a urinary tract infection. This case underlines the possibility of serious adverse drug reactions of nitrofurantoin-induced pulmonary eosinophilia even with such common dosage and treatment duration. The existing complexity in the patient's history (DM type 2, CKD stage 4, COPD) may have predisposed them to develop NIPE. It highlights the need for close follow-up for adverse e.. Read More»
  

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