International Journal of Nanotechnology and Nanomedicine(IJNN)

University of Utah College of Health, Salt Lake City, UT, USA

Publications

• Research Article   
  Lipid Nanocarriers for Targeted Repigmentation in Vitiligo: Advances in Melanocyte Modulation and Topical Delivery
  Author(s): Andres D Parga* and Benjamin Ray
  
  Background: Vitiligo is a chronic autoimmune depigmenting disorder characterized by the loss of functional melanocytes. Current treatments, including corticosteroids, calcineurin inhibitors, and Janus kinase inhibitors, often fail to induce complete or sustained repigmentation due to poor skin penetration and inadequate targeting of melanocyte reservoirs. There is a growing need for precision delivery systems that address the multifactorial pathophysiology of vitiligo, including immune-mediated destruction, oxidative stress, and melanocyte stem cell depletion. Objective: To evaluate the therapeutic potential of lipid-based nanocarriers, such as liposomes, ethosomes, solid lipid nanoparticles, and nanostructured lipid carriers, for targeted delivery of agents that modulate melanocyte survival and promote pigment restoration in vitiligo. .. Read More»
  

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