Ashish Mathur
Associate Professor, Department of Anaesthesiology, G.R. Medical College, Gwalior, Madhya Pradesh, India
Publications
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Research Article
“Comparison of Preemptive Intravenous Paracetamol, Paracetamol–Diclofenac, and Paracetamol–Ketorolac for Postoperative Analgesia Following Elective Abdominal Surgery under General Anaesthesia: A Prospective Randomized Double-Blind Study”
Author(s): Neha Parmar*, Sandeep Singh Jadon, Ashish Mathur and Preeti Goyal
Background: Effective postoperative pain management is an essential component of perioperative care. Preemptive analgesia, as a part of multimodal analgesic strategies, aims to reduce central sensitization and postoperative pain while minimizing opioid requirements. Paracetamol, diclofenac, and ketorolac are commonly used non-opioid analgesics; however, comparative evidence regarding their preemptive combinations remains limited. This study evaluated the efficacy of intravenous paracetamol alone, paracetamol–diclofenac, and paracetamol–ketorolac combinations in patients undergoing elective abdominal surgery under general anaesthesia. Methods: In this prospective, randomized, double-blind study, 99 patients aged 20–60 years with American Society of Anesthesiologists (ASA) physical status I–II undergoing elect.. Read More»