Advancements in Journal of Urology and Nephrology(AJUN)

University of Texas at Dallas, USA

Publications

• Case Report   
  The Silent Risk in ‘Natural’ Health Products
  Author(s): Amith Siripurapu* and Suresh Kankanala
  
  Drug induced liver injury (DILI) is a rapid loss of hepatic function in a person and is clinically diagnosed by jaundice and elevated liver enzymes; It is caused by hepatotoxic medications such as acetaminophen. This case report is of a patient who is a 60 year female with a history of positive ANA who presents the clinic with jaundice and full body pruritic rashes. She has been to urgent care twice in the last couple of months where medrol dose packs and injections were given. She admits this helps, but symptoms resume once the steroid course is completed. Laboratory evaluation showed cholestasis with elevations in alkaline phosphatase (911 U/L), total bilirubin (6.2 mg/dL), and alongside macrocytosis (MCV 106.8 fL). Despite positive autoimmune markers (ANA/AMA 1:160) which initially raised concern for autoimmune etiology, a liver biopsy confirmed DILI. Further interrogation revealed.. Read More»
  

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