International Journal of Clinical & Experimental Dermatology(IJCED)
ISSN: 2476-2415 | DOI: 10.33140/IJCED
Impact Factor: 1.9
Alexandre Reeber
Core Biogenesis SAS, 8c rue Schertz, 67100 Strasbourg, France
Publications
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Review Article
A 2% Oleosome-FGF-2 Fusion Extract Scalp Serum Improves Photo-trichogram-Derived Hair Density, Anagen/Telogen Ratio, Hair Shaft Thickness, and Scalp Barrier Parameters in Women with Shedding-Prone Hair: A Randomized, Single-Blind, Placebo-Controlled Pilot Study
Author(s): Alexandre Reeber*, Monica Bucchia, Samuele Burastero and Marzia Baldi
Background: Hair shedding, reduced perceived hair density, brittle hair prone to falling, and scalp discom-fort are common concerns in women. Objective instrumental methods such as digital phototrichogram can quantify hair density, anagen/telogen ratio, and hair shaft diameter, while scalp hydration, transepidermal water loss (TEWL), and sebum measurements can characterize scalp barrier status. Objective: To evaluate the efficacy of a 2% Oleosome-FGF-2 fusion extract scalp serum compared with placebo on hair density, anagen/telogen ratio, hair shaft thickness, and scalp biophysical parameters over 84 days. Methods: This randomized, single-blind, placebo-controlled pilot study enrolled 40 healthy female volunteers with telogen effluvium and/or brittle hair prone to falling out, ideally with dry or sensitive scalps. Participants received eithe.. Read More»