Advances in Bioengineering and Biomedical Science Research(ABBSR)
ISSN: 2640-4133 | DOI: 10.33140/ABBSR
Impact Factor: 1.7
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Role of RAGE, sRAGE & esRAGE In Inflammation & Diseases
Abstract
Myat Thu Thu Win, Christina Gelknight and Jeevan Matada Basavarajaiah
Receptor for advanced glycation end product (RAGE) is a mutliligand pro-inflammatory pattern recognition receptor (PRR) and plays a role in in many pathologic conditions like diabetes, cancer, cardiovascular and neurodegenerative diseases. It belongs to the immunoglobulin superfamily of cell surface molecules and contains one V-type and two C-type immunoglobulin (Ig) domains in extracellular region [1-3].