Mesencheymal Stem Cell Therapy for Supraspinatus Tendon Rupture Healing: A Case Report of Successful Regeneration

Abstract

Jaqueline Vega Trejo

A 45-year-old male presented with chronic right shoulder pain and mild limitation of motion. Baseline MRI demonstrated supraspinatus tendinitis with a partial-thickness tear,subacromial-subdeltoid bursitis, and inflammatory acromioclavicular joint changes. The patient received an ultrasound-guided intra-articular injection of 50 million mesenchymal stem cells combined with platelet-rich plasma (PRP), followed by a structured rehabilitation program. At 13 months and 25 days post-treatment, follow-up MRI showed resolution of the partial supraspinatus tear with persistent mild tendinopathy and no evidence of structural deterioration. Clinical symptoms and shoulder function also improved, suggesting a favorable response to treatment.

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