Intrahepatic Cholestasis of Pregnancy: Case Report and Review of the Literature

Abstract

Miguel Mansilla-Polo, Blanca Novillo-Del Álamo, Miguel Ángel Navarro-Mira, Carlos Abril-Pérez, Daniel Martín-Torregrosa, Mónica Pozuelo-Ruíz, Ignacio Torres-Navarro, Rafael Botella-Estrada

Gestational cholestasis of pregnancy is a dermatosis of pregnancy clinically characterized by the appearance, more frequent in the third trimester of pregnancy of pruritus, predominantly palmoplantar and nocturnal. Organically, it is associated with elevation of cholestasis enzymes and, especially, bile acids. Given its suspicion, and due to the risk of fetal involvement, ma- ternal-fetal evaluation by an obstetrician is essential and initiation of treatment with ursodeoxycholic acid. We present the clinical case and a narrative review of this entity. Knowledge of it is essential for every doctor since its early diagnosis and treatment allows less fetal morbidity and mortality.

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