Journal of Genetic Engineering and Biotechnology Research(JGEBR)
ISSN: 2690-912X | DOI: 10.33140/JGEBR
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Cranio Facial Manifestations of Solitary Median Maxillary Central Incisor Syndrome: A Case Report
Abstract
Ben Arbia Chayma, Chouchene Farah, Masmoudi Fatma, Baaziz Ahlem, Maatouk Fethi, Ghedira Hichem
This case report was planned according to the CARE Guidelines Solitary Median Maxillary Central Incisor Syndrome (SMMCI) is a rare developmental abnormality occurring in utero from the 35th-38th day after the conception [1,2].
The SMMCI is a very complex malformation involving different development distortions of the midline structures. These development abnormalities occur in utero at 4 to 5 weeks of pregnancy. Defects may involve maxillary and cranial bones, nasal cavity (mid-nasal stenosis, nasal pyriform, choanal atresia) and midline brain structures associated with an increased risk of pituity malformation and malfunction [3,4].