Ascorbic Acid, Still Controversial in Using against Cancer Resistance?

Abstract

Muhammad Torequl Islam

Ascorbic acid is a known strong antioxidant and is evident to exert a pro-oxidative effect of high concentration/dose. Therefore, it can be used not only as a protective agent, but also as an adjuvant or direct cytotoxic agent. Resistance of cancer cells is a regular matter, stimulating scientist to search fighting tools against it. Evidences suggest that the use of ascorbic acid in cancer resistance is still controversial. This paper sketches a current scenario of ascorbic acid in cancer resistance, especially resistance occurring from chemotherapy and radiotherapy. Although, hopes are alive with the use of this vitamin in this case, but more research is needed to understand the fact clearly

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